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Updated: Jan 22, 2026
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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
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Large choroidal melanoma presenting as neovascular glaucoma.
Sabin Sahu1, Tshering Wangchuk Bhutia1, Varun Shrestha1
1Sagarmatha Choudhary Eye Hospital, Siraha, Nepal.
GMS Ophthalmology Cases
|July 12, 2019
Summary
Malignant choroidal melanoma, a rare eye tumor, can mimic neovascular glaucoma. Early diagnosis is crucial, as this condition may present with glaucoma symptoms, necessitating thorough investigation to rule out intraocular malignancy.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Choroidal melanoma is the most common primary eye malignancy in adults, often presenting with poor prognosis.
- It can manifest with various ocular conditions, including secondary glaucoma and uveitis.
Observation:
- A 28-year-old male presented with neovascular glaucoma in his right eye, initially treated medically.
- Ocular ultrasonography revealed a mushroom-shaped lesion suggestive of choroidal melanoma.
- Histopathology confirmed malignant choroidal melanoma after eye enucleation.
Findings:
- Large choroidal melanomas can rarely present with neovascular glaucoma symptoms.
- This case highlights an unusual presentation of a common adult intraocular malignancy.
Implications:
- Investigating the etiology of neovascular glaucoma is critical.
- Ophthalmologists must consider and exclude intraocular tumors, even in rare presentations, to prevent delayed diagnosis of potentially life-threatening conditions.
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