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Filifactor alocis and Dialister pneumosintes in a Mexican population affected by periodontitis and rheumatoid

José Luis Ayala Herrera1,2, Luis Apreza Patrón2, Rita Elizabeth Martínez Martínez2

  • 1School of Dentistry, De La Salle University, León México, Avenida Universidad 602, Colonia Lomas del Campestre, León, 37150, Guanajuato, Mexico.

Microbiology and Immunology
|July 12, 2019
PubMed

Insights

Filifactor alocis and Dialister pneumosintes bacteria were more frequent in periodontitis (PE) patients. These bacteria may worsen periodontal disease (PD) and clinical attachment loss (CAL) in patients with co-occurring PE and rheumatoid arthritis (RA).

Area of Science:

  • Microbiology
  • Periodontology
  • Rheumatology

Background:

  • Filifactor alocis and Dialister pneumosintes are linked to periodontitis (PE) initiation and progression.
  • Investigating the prevalence of these bacteria in patients with PE, rheumatoid arthritis (RA), and both conditions simultaneously is crucial.

Purpose of the Study:

  • To determine and compare the frequency of F. alocis and D. pneumosintes in patients with PE, RA, and PE/RA.
  • To assess the association of these bacteria with periodontal parameters like pocket depth (PD) and clinical attachment loss (CAL).

Main Methods:

  • Polymerase chain reaction (PCR) was used to detect F. alocis and D. pneumosintes in subgingival biofilm samples.
  • Clinical periodontal parameters (PD, CAL) were measured in all patient groups.

Main Results:

  • Bacteria were more frequent in patients diagnosed with PE.
  • Patients with co-occurring PE and RA exhibited significantly higher PD and CAL.
  • A potential influence of F. alocis and D. pneumosintes on PD and CAL was observed.

Conclusions:

  • F. alocis and D. pneumosintes are frequently detected in patients with periodontitis.
  • These bacteria may play a role in the progression of periodontal disease, particularly in individuals with rheumatoid arthritis.
  • Further research is warranted to elucidate the specific mechanisms by which these bacteria impact periodontal health in the context of RA.
Keywords:
periodontal pathogensperiodontitisrheumatoid arthritis

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