Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Schizophrenia01:17

Schizophrenia

824
Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those...
824
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

533
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
533
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

492
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
492
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

499
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
499
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

514
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
514
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

580
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
580

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

When systems fail: institutional responsibility for physician suicide.

European archives of psychiatry and clinical neuroscience·2026
Same author

Alcohol as a Foreseeable Suicide Risk Amplifier.

Acta psychiatrica Scandinavica·2026
Same author

Suicide Risk and Resilience in Stock Market Investors and Traders: Clinical and Medico-Legal Considerations.

Behavioral sciences (Basel, Switzerland)·2026
Same author

Progesterone and suicidal behavior.

QJM : monthly journal of the Association of Physicians·2026
Same author

Another casualty of war: Using the stress-diathesis model to conceptualize a combat veteran suicide death.

Psychiatria Danubina·2026
Same author

Suicide risk and malpractice considerations in geriatric care.

European archives of psychiatry and clinical neuroscience·2026

Related Experiment Video

Updated: Jan 22, 2026

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

7.0K

Suicide in Schizophrenia: An Educational Overview.

Leo Sher1,2, René S Kahn3,4

  • 1James J. Peters Veterans' Administration Medical Center, Bronx, New York, NY 10468, USA. Leo.Sher@mssm.edu.

Medicina (Kaunas, Lithuania)
|July 13, 2019
PubMed
Summary

Suicide is a significant public health issue, with individuals with schizophrenia facing a 10% lifetime risk. Comprehensive treatment is the only proven protective factor against suicidal behavior in this population.

Keywords:
antipsychoticsdepressionschizophreniasuicide

More Related Videos

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.4K
Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research
07:05

Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research

Published on: January 16, 2026

187

Related Experiment Videos

Last Updated: Jan 22, 2026

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management
06:40

The Dyspepsia Educational Tool As a Novel Aid in Dyspepsia Management

Published on: June 29, 2019

7.0K
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
05:51

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia

Published on: June 15, 2011

26.4K
Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research
07:05

Clear Resin Casting of Arthropods for Use in Education, Outreach, and Research

Published on: January 16, 2026

187

Area of Science:

  • Psychiatry
  • Public Health
  • Neuroscience

Background:

  • Suicide is a major public health concern, frequently linked to mood and psychotic disorders.
  • Schizophrenia significantly contributes to reduced life expectancy due to high suicide rates.

Purpose of the Study:

  • To offer an educational overview of suicidal behavior in individuals diagnosed with schizophrenia.
  • To identify risk and protective factors associated with suicide in schizophrenia patients.

Main Methods:

  • Literature review and synthesis of existing research on suicide in schizophrenia.
  • Analysis of demographic, psychosocial, and clinical factors influencing suicide risk.

Main Results:

  • Individuals with schizophrenia have a 10% lifetime suicide rate, a leading cause of premature death.
  • Risk factors include younger age, male gender, unemployment, substance misuse, comorbid depression, and poor treatment adherence.
  • Awareness of specific symptoms like delusions and negative affect, alongside access to lethal means, increases risk.

Conclusions:

  • Early recognition of at-risk individuals and effective management of psychotic symptoms are crucial for suicide prevention.
  • Addressing comorbid depression and substance misuse, alongside promoting treatment compliance, are vital components of comprehensive care.
  • Ongoing monitoring and intervention are necessary throughout the lifespan of individuals with schizophrenia due to persistent elevated suicide risk.