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Updated: Jan 22, 2026

Establishment of Gastric Cancer Patient-derived Xenograft Models and Primary Cell Lines
Published on: July 19, 2019
[Clinical Experience of Patients with Metastatic Gastric Cancer Treated Using Nab-PTX plus RAM chemotherapy]
Takayuki Kuga1, Yuka Yano, Yuuya Tanaka
1Dept. of Surgery, Nagato General Hospital.
Abstract:
The present study reports the outcomes of chemotherapy using nab-PTXplus RAM in 6 patients with metastatic gastric cancer as recommended in the JGCA guidelines for special conditions. Four cases exhibited Grade 3 neutropenia, 1 exhibited Grade 3 hypertension, and no case developed febrile neutropenia; however, the adverse events were tolerated. One case showed partial response, 1 showed stable disease, 2 cases showed non-complete response/non-progressive disease, and 2 cases could not be evaluated. These results suggest that this treatment may be performed safely in ambulatory patients.
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