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A Life Threatening Subglottic and Mediastinal Hemangioma in an Infant
Serap Sahin Onder1, Ozgul Gergin, Burak Karabulut
1Umraniye Research and Education Hospital. Department of Otolaryngology, Istanbul, Turkey.
Insights
Propranolol effectively treats life-threatening infantile hemangiomas in the airway. This non-invasive approach avoids surgery for subglottic hemangiomas, offering a safe first-line option.
Area of Science:
- Pediatric Oncology
- Vascular Malformations
- Pediatric Surgery
Background:
- Subglottic and mediastinal hemangiomas are rare, benign vascular tumors in children.
- These conditions can cause life-threatening airway obstruction requiring medical intervention.
- Existing treatments have variable success rates and potential complications.
Observation:
- A 2-month-old infant presented with stridor due to mediastinal and subglottic hemangioma.
- The infant was treated with propranolol, a beta-blocker medication.
- No surgical intervention or tracheostomy was necessary.
Findings:
- Propranolol demonstrated efficacy in treating the infant's airway-compressing hemangioma.
- The treatment was associated with no reported side effects.
- This case highlights propranolol as a successful non-invasive therapeutic option.
Implications:
- Propranolol represents a safe and effective first-line treatment for infantile hemangiomas affecting the airway.
- Non-invasive management with propranolol can prevent the need for tracheostomy or surgery.
- This approach offers a favorable risk-benefit profile for pediatric patients with subglottic hemangiomas.
Abstract:
Subglottic and mediastinal hemangioma are rare benign vascular tumors of childhood. They cause potentially life threatening condition which requires intervention. Several therapeutic options have been described in the literature with varying degrees of success and complications. We report a case of a stridulous 2-month old female infant with mediastinal and subglottic hemangioma. The child was treated with propranolol without the need for tracheostomy or any other surgical intervention, and with no reported side effects. Propranolol is an effective, non-invasive treatment for life threatening infantile hemangiomas compressing the airway, should be used as a firstline treatment for subglottic hemangiomas when intervention is required.
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