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Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Comorbidity burden in systemic sclerosis: beyond disease-specific complications.
Eleni Pagkopoulou1, Alexandra Arvanitaki2, Dimitrios Daoussis3
1Fourth Department of Internal Medicine, Hippokration University Hospital, Medical School, Aristotle University of Thessaloniki, 49 Konstantinoupoleos Str, 54642, Thessaloniki, Greece.
Systemic sclerosis (SSc) patients frequently experience significant comorbidities like cardiovascular disease, infections, and cancer. Early recognition and management of these conditions are crucial for improving life expectancy in SSc.
Area of Science:
- Rheumatology and Immunology
- Cardiology
- Oncology
Background:
- Systemic sclerosis (SSc) is a chronic autoimmune disease marked by widespread fibrosis and vasculopathy.
- SSc patients face severe organ damage and a high prevalence of comorbidities impacting prognosis.
Purpose of the Study:
- To review the occurrence and clinical significance of comorbidities in Systemic Sclerosis.
- To guide rheumatologists in managing these comorbidities in daily practice.
Main Methods:
- Narrative review based on published recommendations.
- Searched MEDLINE and EMBASE databases for relevant keywords.
Main Results:
- Cardiovascular disease, infections, and cancer are highly prevalent and impact SSc patient life expectancy.
- Psychological disorders are also common, affecting emotional and mental health.
- Data on comorbidities in SSc are often inconclusive but highlight significant health challenges.
Conclusions:
- Comorbidities significantly affect Systemic Sclerosis patient outcomes and quality of life.
- Integrated management strategies are needed to address the complex health needs of SSc patients.
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