Prevalence of Cerebral Palsy in Indian Children: A Systematic Review and Meta-Analysis

Anil Chauhan1, Manvi Singh2, Nishant Jaiswal1,2

  • 1Evidence Based Health Informatics Unit, Regional Resource Centre, Department of Telemedicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Insights

The pooled prevalence of cerebral palsy in Indian children is 2.95 per 1000. This systematic review highlights the need for better data and policy adjustments for cerebral palsy prevention and management in India.

Area of Science:

  • Pediatrics
  • Neurology
  • Public Health

Background:

  • Cerebral palsy (CP) is a group of disorders affecting movement and posture, posing a significant health challenge globally.
  • Accurate prevalence data is crucial for effective resource allocation and policy development in public health initiatives.
  • Understanding the epidemiology of CP in India is vital due to its large child population.

Purpose of the Study:

  • To determine the pooled prevalence of cerebral palsy (CP) among children in India.
  • To synthesize existing data on CP prevalence to inform public health strategies.
  • To identify research gaps in the study of CP in the Indian context.

Main Methods:

  • A systematic literature search was conducted across PubMed, Ovid SP, and EMBASE, including unpublished data.
  • Prospective, retrospective, cross-sectional, and cohort studies focusing on Indian children with CP were screened.
  • Data extraction and quality assessment were performed, with analysis using STATA MP12.

Main Results:

  • Eight studies, out of 862 initially searched, met the inclusion criteria for quantitative analysis.
  • The overall pooled prevalence of cerebral palsy in Indian children was found to be 2.95 per 1000 (95% CI 2.03-3.88).
  • Sub-group analyses revealed pooled prevalence rates of 1.83 (rural), 2.29 (urban), and 4.37 (mixed rural-urban) per 1000 children.

Conclusions:

  • A significant paucity of high-quality prevalence studies on cerebral palsy in India was identified.
  • The observed prevalence of cerebral palsy in India is comparable to global estimates.
  • There is an urgent need to re-evaluate resource allocation and policy implementation for CP prevention and management based on current disease burden.
Abstract

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