Related Experiment Video
Updated: Jan 22, 2026

07:36
Studying Cavitation Enhanced Therapy
Published on: April 9, 2021
5.8K
Intrachoroidal cavitation in myopic eyes
Ramesh Venkatesh1, Kushagra Jain2, Aditya Aseem2
1Department of Retina and Vitreous, Narayana Nethralaya, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore, 560080, India. vramesh80@yahoo.com.
International Ophthalmology
|July 14, 2019
Summary
Intrachoroidal cavitation (ICC) is prevalent in highly myopic eyes, often associated with focal chorioretinal atrophy and intrascleral vessels. Early detection and monitoring are crucial for managing potential complications in these eyes.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Science
Background:
- High myopia is a significant risk factor for various ocular pathologies.
- Intrachoroidal cavitation (ICC) is a less understood finding in the context of myopia.
- Understanding ICC's characteristics is vital for managing myopic eyes.
Purpose of the Study:
- To investigate the incidence and specific features of intrachoroidal cavitation (ICC).
- To determine the association of ICC with pathological myopia (PM).
- To identify ocular characteristics linked to the presence of ICC in high myopia.
Main Methods:
- Retrospective analysis of 108 eyes with and without pathological myopia (PM).
- PM defined by refractive error (≥-6.0 D) or axial length (≥26 mm).
- Optical Coherence Tomography (OCT) used to assess for ICC and associated features like chorioretinal atrophy and posterior staphyloma.
Main Results:
- ICC was observed in 55.8% of highly myopic eyes.
- Focal/patchy chorioretinal atrophy (CRA) and intrascleral vessels were significantly associated with ICC (p=0.005 and p=0.018, respectively).
- Fluid transudation from dilated intrascleral vessels may contribute to ICC development.
Conclusions:
- ICC is a common finding in pathological myopia, linked to focal CRA and intrascleral vessels.
- ICC may indicate subtle changes in scleral contour and contribute to posterior staphyloma.
- Regular follow-up is recommended for myopic eyes with CRA or myopic conus to monitor for ICC development.
Related Concept Videos
Muscles of the Eye
4.0K
The muscles of the eye are sophisticated structures that control eye movement and focus, allowing for the precise and rapid adjustments necessary for vision. The human eye is controlled by ten muscles — six extraocular muscles, three intraocular muscles, and one primary eyelid retractor muscle.
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
Extraocular Muscles
The six extraocular muscles surround the eyeball and control its movements. They are responsible for a wide range of eye motions, including looking up, down, left, right, and...
4.0K
Accessory Structures of the Eye
3.4K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
3.4K
Focusing of Light in the Eye
5.5K
Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
5.5K
Vision
59.5K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
59.5K
Genetic Lingo
114.1K
Overview
114.1K
Position-effect Variegation
7.0K
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
7.0K

