Evolutionary responses of mutualistic insect-bacterial symbioses in a world of fluctuating temperatures

Climate change is altering the abundance and distribution of millions of insect species around the world and is a major contributor to the decline of numerous species. Many insect species may be indirectly affected through their nutritional dependence on mutualistic bacteria. Indeed, these bacterial partners generally have a highly reduced and static genome, resulting from millions of years of coevolution and isolation in insect cells, and have limited adaptive capacity. The dependence of insects on bacterial partners with narrow environmental tolerance also restricts their ability to adapt, potentially increasing the risk of their extinction, particularly in a world characterized by increasing and fluctuating temperatures. In this review, we examine how climate change can affect the evolutionary trajectories of bacterial mutualism in insects by considering the possible alternatives that may compensate for the dependence on bacterial partners that have become 'Achilles' heels'. We also discuss the beneficial and compensatory effects, as well as the antagonistic effects associated with so-called facultative symbionts in the context of an increased incidence of transient extreme temperatures.