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Related Concept Videos

Weak Base Solutions03:21

Weak Base Solutions

24.9K
Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
24.9K
Weak Acid Solutions04:02

Weak Acid Solutions

42.3K
Few compounds act as strong acids. A far greater number of compounds behave as weak acids and only partially react with water, leaving a large majority of dissolved molecules in their original form and generating a relatively small amount of hydronium ions. Weak acids are commonly encountered in nature, being the substances partly responsible for the tangy taste of citrus fruits, the stinging sensation of insect bites, and the unpleasant smells associated with body odor. A familiar example of a...
42.3K
Titration of a Weak Acid with a Weak Base01:08

Titration of a Weak Acid with a Weak Base

4.8K
Weak acids and bases do not undergo dissociation completely, and titrations between these two are rarely studied. When such studies are performed, say, for the titration of a weak acid with a weak base, the titration curve plots the change in pH as a function of the volume of base added. Take the titration of acetic acid with ammonia, for instance. During the titration, these two species form ammonium acetate and water, but the pH change is slow and gradual.
As a result, there is no simple...
4.8K
Titration Calculations: Weak Acid - Strong Base03:55

Titration Calculations: Weak Acid - Strong Base

49.1K
Calculating pH for Titration Solutions: Weak Acid/Strong Base
For the titration of 25.00 mL of 0.100 M CH3CO2H with 0.100 M NaOH, the reaction can be represented as:
49.1K
Titration of a Weak Acid with a Strong Base01:30

Titration of a Weak Acid with a Strong Base

4.3K
In titrating a weak acid with a strong base, different calculation methods are applied at various stages. Initially, the pH of a weak acid like acetic acid is calculated using its dissociation constant (Ka) and an ICE table. Upon addition of a strong base such as sodium hydroxide, a buffer forms, and its pH is determined using the Henderson-Hasselbalch equation. As more base is added and the titration reaches the halfway point, the pH becomes equal to the pKa of the acid, indicating equal...
4.3K
Titration of a Weak Base with a Strong Acid01:20

Titration of a Weak Base with a Strong Acid

8.6K
The titration curve of a weak base like ammonia with a strong acid like hydrochloric acid is the mirror image of the titration curve of a weak acid with a strong base.
Using the ICE table and substituting the Kb value, we calculate the initial pH of 50 mL of 0.1 M ammonia to be 11.11. Addition of 25 mL of 0.1 M hydrochloric acid to this solution of ammonia results in a buffer with an equal concentration of ammonia and ammonium ions. The pH of this buffer can be calculated by substituting these...
8.6K

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Long-term Behavioral Tracking of Freely Swimming Weakly Electric Fish
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[A case with a novel weak D type].

Yunlei He1, Lu Yu, Deyi Xu

  • 1Ningbo Central Blood Station, Zhejiang 315000, China. 80625346@qq.com.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics
|July 15, 2019
PubMed
Summary
This summary is machine-generated.

A new weak D type, RHD (1022T>A), was identified in a Chinese blood donor. This finding expands the known diversity of RhD alleles in this population.

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Area of Science:

  • Genetics
  • Immunology
  • Hematology

Background:

  • The Rh blood group system is crucial for transfusion medicine.
  • Weak D phenotypes can lead to transfusion complications.
  • Characterizing novel RhD alleles is important for blood safety.

Purpose of the Study:

  • To report the identification of a novel weak D allele in a Chinese individual.
  • To characterize the serological and genetic features of this new allele.

Main Methods:

  • Serological testing of RhD epitopes.
  • Sequencing of the RHD gene (10 exons and flanking introns).
  • RHD zygosity determination using sequence-specific primer PCR.

Main Results:

  • A novel RHD allele, RHD (1022T>A), was identified.
  • The subject presented with a weak D phenotype.
  • Serological analysis confirmed the weak D phenotype associated with the novel allele.

Conclusions:

  • A novel weak D allele has been identified in the Chinese population.
  • This discovery contributes to the understanding of RhD polymorphism.
  • Further studies are needed to assess the clinical significance and prevalence.