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[Chinese expert consensus on diagnosis and treatment of perianal necrotizing fasciitis (2019)]
Abstract:
Perianal necrotizing fasciitis is a serious soft tissue infectious disease of perianal and perineal regions, where a synergistic action of multiple bacteria (including aerobic bacteria and anaerobic bacteria) results in suppurative necrosis of the skin and soft tissue. The disease progress may rapidly cause systemic sepsis through blood circulation, often with complicating shock and MODS, or death. Any delay in diagnosis and treatment of early acute infections may lead to higher mortality because of lack of standardized treatment. The Clinical Guidelines Committee aims to formulate expert consensus on the treatment of perianal necrotizing fasciitis in terms of etiology and pathology, clinical manifestations, laboratory and imaging study, preoperative preparation, surgical treatment (the application of antibiotics, the timing and key points of debridement, assistant therapy), postoperative wound care, nutritional support, surgical reconstruction and rehabilitation. This consensus is a reference for clinicians based on patient conditions.
Insights
Perianal necrotizing fasciitis, a severe bacterial infection, requires prompt, standardized treatment to prevent sepsis and death. This expert consensus provides clinical guidelines for effective management of this critical condition.
Area of Science:
- Infectious Diseases
- Surgical Pathology
Background:
- Perianal necrotizing fasciitis is a rapidly progressive, life-threatening soft tissue infection.
- Synergistic bacterial action leads to extensive tissue necrosis and potential systemic sepsis.
- Lack of standardized treatment protocols contributes to high mortality rates.
Purpose of the Study:
- To establish an expert consensus on the diagnosis and treatment of perianal necrotizing fasciitis.
- To provide a clinical reference for healthcare professionals managing this condition.
- To outline a comprehensive approach from etiology to rehabilitation.
Main Methods:
- Literature review and expert panel discussion.
- Development of evidence-based recommendations for clinical practice.
- Consensus formulation on etiology, pathology, diagnosis, and treatment strategies.
Main Results:
- Detailed guidelines covering etiology, clinical presentation, diagnostics, and preoperative preparation.
- Recommendations for surgical treatment, including antibiotics, debridement, and adjuvant therapies.
- Guidance on postoperative wound care, nutritional support, reconstruction, and rehabilitation.
Conclusions:
- Standardized, timely management is crucial for improving outcomes in perianal necrotizing fasciitis.
- This consensus serves as a vital reference for clinicians, promoting consistent and effective patient care.
- Adherence to these guidelines can reduce mortality and enhance patient recovery.
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