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New antibiotics 4181-A and B from Streptomyces griseus; taxonomy, fermentation, isolation and characterization
T Otani1, I Yamawaki, H Matsumoto
1Biological Research Laboratory, Taiho Pharmaceutical Co., Ltd., Tokushima, Japan.
The Journal of Antibiotics
|March 1, 1988
Abstract:
The new antibiotics 4181-A and B were isolated from the fermentation broth of Streptomyces griseus, a soil isolate. Their molecular formulae were determined as C29H21NO9 and C28H19NO9, respectively. The UV, IR and NMR spectra suggest that they possess a quinone moiety in their structures. They were found to have antibacterial, antifungal and antitumor activity.