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Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation
Published on: October 31, 2019
Draft genome sequence data of Bifidobacterium longum strain VKPM Ac-1636, a prospective probiotic isolated from human
V V Zinina1, A A Korzhenkov1, A V Tepliuk1
1National Research Center "Kurchatov Institute", Moscow 123182, Russia.
Insights
The draft genome of Bifidobacterium longum subsp. longum Ac-1636, isolated from a healthy infant, reveals probiotic properties. This data supports its potential use in developing novel probiotics and functional foods.
Area of Science:
- Microbiology
- Genomics
Background:
- Bifidobacterium longum is a key gut commensal in infants.
- Probiotic bacteria offer health benefits and are used in functional foods.
- Strain Ac-1636 was isolated from a healthy one-year-old infant's digestive tract.
Purpose of the Study:
- To present the draft genome sequence of Bifidobacterium longum subsp. longum strain Ac-1636.
- To identify genetic determinants associated with probiotic potential.
- To make the genome data publicly accessible for further research.
Main Methods:
- Whole-genome sequencing of Bifidobacterium longum subsp. longum Ac-1636.
- Bioinformatic analysis and genome annotation.
- Deposit of sequence data in public repositories (DBJ/EMBL/GenBank).
Main Results:
- The draft genome size is 2,321,741 bp, comprising 73 scaffolds with an N50 of 162,253 bp.
- Genome annotation identified multiple genes conferring probiotic properties.
- The genome sequence is available under accession numbers RZHL00000000, PRJNA511803, and SAMN10644101.
Conclusions:
- The genome sequence of Bifidobacterium longum subsp. longum Ac-1636 provides valuable insights into its probiotic capabilities.
- This strain holds promise for the development of new probiotic products and foods.
- Public availability of the genome data facilitates future research and application.
Abstract:
Data on the draft genome sequence of Bifidobacterium longumsubsp. longum strain Ac-1636 is presented in this report. This strain, isolated from the digestive tract of one-year old healthy infant, was deposited in the Russian National Collection of Industrial Microorganisms as a prospective candidate for development of probiotics and probiotic foods. The 2,321,741 bp draft genome consists of 73 scaffolds with N50 of 162,253 bp. Genome annotation revealed the presence of multiple determinants of probiotic properties of this strain. The draft genome sequence data of strainAc-1636 is available in DBJ/EMBL/GenBank under the accession nos. RZHL00000000, PRJNA511803 and SAMN10644101 for Genome, Bioproject and Biosample, respectively.
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