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Association of interarm blood pressure difference with cardio-cerebral vascular disease: A community-based,

Siyu Yu1, Yi Zhou1, Kang Wu1

  • 1Department of Chronic Disease, Shanghai Pudong New Area Center for Disease Control and Prevention, Pudong Institute of Preventive Medicine, Fudan University, Pudong New Area, Shanghai, China.

Journal of Clinical Hypertension (Greenwich, Conn.)
|July 16, 2019
PubMed

Insights

Interarm blood pressure difference (IAD) is linked to higher stroke and coronary heart disease risks in a Chinese community. Elevated diastolic IAD (dIAD) showed significant associations with these cardiovascular conditions.

Area of Science:

  • Cardiovascular epidemiology
  • Vascular health assessment

Background:

  • Interarm blood pressure difference (IAD) is an established risk factor for peripheral artery disease and cardio-cerebral vascular disease (CCVD).
  • Understanding IAD's association with specific cardiovascular outcomes like stroke and coronary heart disease (CHD) is crucial for public health in diverse populations.

Purpose of the Study:

  • To investigate the association between interarm blood pressure difference (systolic and diastolic) and the prevalence of stroke and coronary heart disease.
  • To evaluate these associations within a Chinese community setting.

Main Methods:

  • A cross-sectional study involving 10,657 residents aged 15+ in Shanghai, China, selected via three-stage random sampling.
  • Systolic and diastolic blood pressure were measured in both arms to calculate interarm blood pressure difference (IAD).
  • Logistic regression models were employed to analyze the relationship between sIAD, dIAD, and the prevalence of stroke and CHD, adjusting for relevant factors.

Main Results:

  • Elevated diastolic interarm blood pressure difference (dIAD) was significantly associated with increased odds of stroke prevalence (OR 1.357 for dIAD ≥20 mmHg; OR 1.702 for dIAD 15-19 mmHg).
  • Higher dIAD levels also showed significant associations with coronary heart disease prevalence (OR 1.726 for dIAD ≥20 mmHg; OR 1.498 for dIAD 15-19 mmHg).
  • The relationship between cardio-cerebral vascular disease and dIAD was statistically significant in this Chinese population.

Conclusions:

  • Diastolic interarm blood pressure difference is significantly associated with the prevalence of stroke and coronary heart disease in a Chinese community.
  • These findings highlight the clinical relevance of measuring IAD for cardiovascular risk assessment.
  • Further prospective cohort studies are recommended to explore the association of varying IAD levels with disease incidence and mortality.

Keywords:
Interarm blood pressure differencecardio-cerebral vascular diseasecoronary heart diseasecross-sectional studystroke

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