Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

55.5K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
55.5K
Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview01:02

Ultraviolet and Visible (UV–Vis) Spectroscopy: Overview

4.5K
Ultraviolet–visible (UV–visible or UV–Vis) spectroscopy is an analytical technique that investigates the interaction between matter and UV–Vis light within the electromagnetic spectrum. This method is widely used for its versatility, simplicity, and relatively quick data acquisition, making it valuable for both qualitative and quantitative analysis. When UV–Vis radiation passes through a material,  molecules absorb light depending on the energy required for...
4.5K
Introduction to Special Senses01:26

Introduction to Special Senses

7.3K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
7.3K
Tactile and Chemical Senses01:27

Tactile and Chemical Senses

732
Tactile senses encompass touch, temperature, and pain, each mediated by specific receptors. Touch receptors detect mechanical energy or pressure against the skin. Sensory fibers from these receptors enter the spinal cord and relay information to the brain stem. Here, most fibers cross over to the opposite side of the brain. The touch information then moves to the thalamus, which projects a map of the body's surface onto the somatosensory areas of the parietal lobes in the cerebral cortex.
732
Gene Regulation in Microbial Communities: Quorum Sensing01:28

Gene Regulation in Microbial Communities: Quorum Sensing

543
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...
543
Immunofluorescence Microscopy01:12

Immunofluorescence Microscopy

13.0K
A fluorescence microscope uses fluorescent chromophores called fluorochromes, which can absorb energy from a light source and then emit this energy as visible light. Fluorochromes include naturally fluorescent substances (such as chlorophylls) and fluorescent stains that are added to the specimen to create contrast. Dyes such as Texas red and FITC are examples of fluorochromes. Other examples include the nucleic acid dyes 4’,6’-diamidino-2-phenylindole (DAPI), and acridine orange.
13.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Single-cell genomic analysis of cancer cells from one treatment-naïve patient with metastatic prostate cancer.

BMC genomic data·2026
Same author

Shock-scattering micro-histotripsy-aided fine needle aspiration for enhanced biomarker profiling and cytopathology.

Nature communications·2026
Same author

Neonatal amygdala and fear processing across early childhood.

European child & adolescent psychiatry·2026
Same author

Predicting clinically significant prostate cancer with or without digital rectal exam and MRI data using ClarityDX Prostate models.

NPJ digital medicine·2026
Same author

Neuroprognostication via Radiomics and Machine Learning Following Neonatal Hypoxic-Ischemic Insult.

The Journal of pediatrics·2026
Same author

Hypoxia restores the acidosis-induced inhibition of cancer cell dissemination.

Cell reports·2026

Related Experiment Video

Updated: Jan 22, 2026

High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning
09:31

High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning

Published on: April 28, 2022

3.5K

Ultraviolet photoacoustic remote sensing microscopy.

Nathaniel J M Haven, Kevan L Bell, Pradyumna Kedarisetti

    Optics Letters
    |July 16, 2019
    PubMed
    Summary

    This study introduces ultraviolet photoacoustic remote sensing microscopy for unstained cell nucleus imaging. This novel technique offers a faster, more reliable alternative to traditional histopathology methods.

    Area of Science:

    • Biomedical Optics
    • Histopathology
    • Microscopy

    Background:

    • Traditional histopathology relies on time-consuming fixation, sectioning, and staining.
    • Staining processes in histopathology can introduce variability and require extensive sample preparation.

    Purpose of the Study:

    • To present a novel microscopy technique for imaging cell nuclei without exogenous stains or labeling.
    • To demonstrate a non-contact, reflection-mode approach for rapid histological analysis.

    Main Methods:

    • Utilized ultraviolet photoacoustic remote sensing microscopy (UV-PARSM).
    • Employed a reflection mode configuration for non-contact imaging.
    • Applied the technique to tumor cell cultures and excised tissue samples.

    More Related Videos

    Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing
    06:16

    Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing

    Published on: April 25, 2019

    8.0K
    Three-dimensional Optical-resolution Photoacoustic Microscopy
    08:31

    Three-dimensional Optical-resolution Photoacoustic Microscopy

    Published on: May 3, 2011

    18.8K

    Related Experiment Videos

    Last Updated: Jan 22, 2026

    High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning
    09:31

    High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning

    Published on: April 28, 2022

    3.5K
    Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing
    06:16

    Femtosecond Laser Filaments for Use in Sub-Diffraction-Limited Imaging and Remote Sensing

    Published on: April 25, 2019

    8.0K
    Three-dimensional Optical-resolution Photoacoustic Microscopy
    08:31

    Three-dimensional Optical-resolution Photoacoustic Microscopy

    Published on: May 3, 2011

    18.8K

    Main Results:

    • Achieved high-resolution imaging at 0.7 μm.
    • Obtained high signal-to-noise ratios, up to 53 dB.
    • Demonstrated close agreement between UV-PARSM images and traditional hematoxylin and eosin staining.

    Conclusions:

    • UV-PARSM enables label-free imaging of cell nuclei, bypassing laborious sample preparation.
    • The non-contact, reflection-mode approach offers a potentially faster and more consistent alternative to conventional histopathology.
    • This technology holds promise for efficient histological information retrieval.