Related Experiment Video
Updated: Jan 22, 2026

Implantation of a New Micro Acoustic Tag in Juvenile Pacific Lamprey and American Eel
Published on: March 16, 2019
Lamellarin Sulfates from the Pacific Tunicate Didemnum ternerratum
Joe Bracegirdle, Luke P Robertson1,2, Paul A Hume
1Environmental Futures Research Institute , Griffith University , Southport 4222 , Gold Coast , Australia.
Abstract:
Six new lamellarin sulfates (1-6) were isolated from the methanolic extract of the Pacific tunicate Didemnum ternerratum, collected from the Kingdom of Tonga. Mass spectrometric molecular networking through the GNPS platform was used to target the isolation of 1-6. Planar structures were elucidated through a combination of NMR and MS experiments. Through comparison of experimental and calculated ECD spectra, the absolute configurations of atropisomers 2-5 were determined, with their energetic barriers to racemization also determined computationally. The cytotoxicity of the compounds was tested against the human colon carcinoma cell line HCT-116, where lamellarin D-8-sulfate (5) exhibited moderate activity with an IC50 of 9.7 μM.
Related Concept Videos
Sulfate Attack on Concrete
Sulfates from sources like soil, groundwater, or industrial effluents...
Phase II Reactions: Sulfation and Conjugation with α-Amino Acids
Keystone Species
Chemical Equations
The Sulfur Cycle
The Extracellular Matrix

