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Histiocytosis X Langerhans cells react with antiinterleukin-2 receptor monoclonal antibody
S Barbey1, P Gane, O Le Pelletier
1Groupe de Pathologie Pédiatrique, Hôpital Necker Enfants Malades, Paris, France.
Pediatric Pathology
|January 1, 1987
Abstract:
Immunohistochemical study of 7 cases of histiocytosis X (HX) and of histologically normal skin shows that HX Langerhans cells react with Bl.49.9 monoclonal antibody which recognizes the Interleukin-2 receptor, whereas normal skin Langerhans cells do not. This reactivity suggest activation of HX Langerhans cells.