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A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
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Association Between First-Trimester Subchorionic Hematomas and Pregnancy Loss in Singleton Pregnancies
Mackenzie N Naert1, Hanaa Khadraoui, Alberto Muniz Rodriguez
1Icahn School of Medicine at Mount Sinai, New York, Touro College of Osteopathic Medicine, Harlem, and Maternal Fetal Medicine Associates, PLLC, New York, New York.
Obstetrics and Gynecology
|July 16, 2019
Summary
A first-trimester subchorionic hematoma in singleton pregnancies is not independently linked to pregnancy loss. This finding suggests other factors may influence early pregnancy outcomes.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Reproductive Health
Background:
- Subchorionic hematomas are common in early pregnancy.
- Their association with pregnancy loss requires further clarification.
Purpose of the Study:
- To assess the association between first-trimester subchorionic hematoma and pregnancy loss in singleton pregnancies.
- To determine if hematoma characteristics influence pregnancy loss risk.
Main Methods:
- Retrospective cohort study of 2,446 women with singleton pregnancies.
- Ultrasound scans between 6 and 14 weeks gestation.
- Logistic regression analysis to control for confounding variables.
Main Results:
- 18.4% of women had subchorionic hematomas.
- Univariable analysis showed an increased risk of pregnancy loss (7.5% vs 4.9%).
- Adjusted analysis found no independent association between subchorionic hematoma and pregnancy loss (aOR 1.13).
Conclusions:
- First-trimester subchorionic hematoma is not independently associated with pregnancy loss before 20 weeks.
- Hematoma characteristics did not predict pregnancy loss in this cohort.
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