Lipid-based nano delivery of antimicrobials to control food-borne bacteria

Direct application of antibacterial agents into foods gives limited advantages because bioactive ingredients may be partially inactivated, neutralized, or easily diffused when contacting with the food matrix. Hence, the aim of this study is to investigate the application of lipid-based nanocarriers as delivery systems for antibacterial ingredients. In this regard, several types of these carriers such as nanoliposomes, nanoemulsions, solid lipid nanoparticles (SLNs), and nanostructured lipid carriers (NLCs) are explored. This study seeks to cover the important challenges of lipid-based nanocarriers including structures and characteristics, properties, production methods, advantages and drawbacks, and their applications to encapsulate antibacterial compounds effectively, particularly in food systems. However, for more scrutiny inspection of the functionality of lipid-based nanocarriers, we have gathered and discussed the studies related to the antibiotic-loaded lipid-based nanoparticles. Also, the role of such nanocarriers in active packaging systems when combining with edible coatings or films is discussed.