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Related Experiment Video

Updated: Jan 22, 2026

MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
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Infantile tremor syndrome: current perspectives.

Rajesh Gupta1, A K Rawat2, Poonam Singh3

  • 1Department of Paediatrics, Government Medical College, Datia, MP, India.

Research and Reports in Tropical Medicine
|July 17, 2019
PubMed
Summary
This summary is machine-generated.

Infantile Tremor Syndrome (ITS) involves tremors, anemia, and developmental issues in infants. While Vitamin B12 deficiency is suspected, management includes nutritional support and medications for tremors.

Keywords:
infantile tremor syndrometremorsundernutritionvitamin B12

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Area of Science:

  • Pediatrics
  • Neurology
  • Nutritional Science

Background:

  • Infantile Tremor Syndrome (ITS) presents with tremors, anemia, skin issues, and developmental regression.
  • The etiology of ITS remains unclear, with infectious, metabolic, and nutritional factors hypothesized.
  • Vitamin B12 deficiency is increasingly considered a potential cause, though not definitively proven.

Purpose of the Study:

  • To summarize the clinical presentation and hypothesized etiologies of Infantile Tremor Syndrome.
  • To discuss current management strategies for ITS, including nutritional supplementation and symptomatic treatment of tremors.

Main Methods:

  • Review of existing literature on Infantile Tremor Syndrome.
  • Analysis of clinical characteristics, proposed causes, and treatment approaches.

Main Results:

  • ITS is a self-limiting condition resolving within 4-6 weeks.
  • Key symptoms include coarse tremors, anemia, pigmentary skin changes, hypotonia, and developmental regression.
  • Management is often empirical, addressing potential nutritional deficiencies and managing tremors.

Conclusions:

  • The exact cause of Infantile Tremor Syndrome is not yet confirmed.
  • Vitamin B12 deficiency is a debated but developing consensus for ITS etiology.
  • Current management focuses on nutritional support (Iron, Calcium, Magnesium, Vitamin B12) and tremor control (e.g., propranolol).