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Sacral nerve stimulation in slow-transit constipation: effectiveness at 5-year follow-up
Michele Schiano di Visconte1, Arianna Pasquali2, Tommaso Cipolat Mis2
1Colorectal and Pelvic Floor Diseases Center, Department of General Surgery, "S. Maria dei Battuti" Hospital, Via Brigata Bisagno 4, 31015, Conegliano, Treviso, Italy. mschianodivisconte@gmail.com.
International Journal of Colorectal Disease
|July 17, 2019
Summary
Sacral nerve stimulation (SNS) shows promising short-term relief for slow-transit constipation (STC) but its long-term effectiveness requires further evaluation due to declining results over time.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Neuromodulation
Background:
- Slow-transit constipation (STC) significantly impacts quality of life.
- Conservative therapies often fail for STC patients.
- Sacral nerve stimulation (SNS) is an emerging treatment option.
Purpose of the Study:
- To assess the short- and long-term efficacy of sacral nerve stimulation (SNS) for treating slow-transit constipation (STC).
Main Methods:
- Retrospective cohort analysis of STC patients unresponsive to conservative treatments.
- Inclusion of patients without concomitant diseases.
- Temporary SNS lead implantation followed by permanent implant for responders (>50% symptom reduction).
Main Results:
- 21 of 25 patients received permanent SNS implants.
- Significant short-term improvement in Cleveland Clinic Constipation Score (CCCS) and colorectal transit time at 6 months.
- Symptom scores improved in the first year but declined long-term.
- 48% neuromodulator removal rate at 60 months.
Conclusions:
- SNS offers promising short-term symptom relief for STC.
- Efficacy of SNS for STC appears to decline beyond the first year.
- Further research is needed to establish the long-term benefits of SNS in STC management.
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