[Neurological complications associated with dengue virus infection]

Area of Science:

• Neurology
• Infectious Diseases
• Virology

Background:

• Dengue is an arboviral infection caused by the dengue virus.
• Neurological complications are a significant concern associated with dengue virus infection.

Purpose of the Study:

• To review the neurological complications associated with dengue virus infection.
• To highlight the neurotropic nature of the dengue virus.

Main Methods:

• Review of epidemiological, case series, and histopathological studies.
• Analysis of reported neurological syndromes, including encephalopathy, encephalitis, and post-infectious syndromes.
• Examination of muscular and ophthalmological complications.

Main Results:

• Neurological complications occur in 5.6-14.6% of dengue cases, more frequently with serotypes 1 and 3.
• Encephalopathy is the most common neurological syndrome (0.5-6%), particularly in children and adolescents.
• Other complications include myelitis, muscular dysfunction (myositis, rhabdomyolysis), stroke (0.26%), and ophthalmological issues.

Conclusions:

• The spectrum of neurological complications from dengue virus is broad.
• Reliable data on the true incidence of these complications are lacking due to reliance on isolated case studies.