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Diagnosis of Ecto- and Endoparasites in Laboratory Rats and Mice
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Ectoparasites: Scabies.

Cristina Thomas1, Sarah J Coates2, Daniel Engelman3

  • 1Departments of Dermatology and Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Journal of the American Academy of Dermatology
|July 17, 2019
PubMed
Summary
This summary is machine-generated.

Scabies, a skin disease caused by mites, is a global health concern. Addressing diagnosis and treatment gaps is crucial for controlling this neglected tropical disease.

Keywords:
Sarcoptes scabieiStaphylococcus aureusStreptococcus pyogenescrusted scabieshomelessimpetigoinfestationivermectinmass drug administrationneglected tropical diseaseoptical coherence tomographypermethrinpoststreptococcal glomerulonephritispruritusreflectance confocal microscopyrefugeerheumatic feverrheumatic heart diseasescabies

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Area of Science:

  • Dermatology
  • Public Health
  • Infectious Diseases

Background:

  • Scabies is an ectoparasitic infection caused by Sarcoptes scabiei var. hominis, posing a significant public health challenge worldwide.
  • Delayed diagnosis in high-income settings can trigger outbreaks, while limited healthcare access in low- and middle-income countries leads to undertreatment and chronic health issues.
  • The World Health Organization now classifies scabies as a neglected tropical disease, prompting focused efforts to improve control strategies.

Purpose of the Study:

  • To provide a comprehensive review of current knowledge on scabies.
  • To update information on scabies epidemiology, clinical presentation, diagnostic methods, and treatment options.
  • To highlight public health considerations essential for effective scabies control.

Main Methods:

  • Systematic review of available scientific literature and data on scabies.
  • Analysis of epidemiological trends, clinical manifestations, and diagnostic challenges.
  • Evaluation of current management strategies and public health interventions.

Main Results:

  • Scabies affects all socioeconomic strata globally, with distinct challenges in different income settings.
  • Effective control is hindered by diagnostic delays and inadequate treatment access.
  • Increased global awareness and targeted interventions are emerging to address these control impediments.

Conclusions:

  • Scabies control requires a multifaceted approach addressing diagnosis, treatment, and public health infrastructure.
  • Recognizing scabies as a neglected tropical disease necessitates intensified research and resource allocation.
  • Systematic efforts are vital to bridge existing gaps and improve patient outcomes and disease management globally.