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Updated: Jan 22, 2026

Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors
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Use of Label-free Optical Biosensors to Detect Modulation of Potassium Channels by G-protein Coupled Receptors

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The signaling proteins GPR158 and RGS7 modulate excitability of L2/3 pyramidal neurons and control A-type potassium

Chenghui Song1, Cesare Orlandi1, Laurie P Sutton1

  • 1Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458.

The Journal of Biological Chemistry
|July 18, 2019
PubMed

Keywords:
G protein-coupled receptor (GPCR)KV4.2 channelsdepressionheterotrimeric G proteinintrinsic excitabilityion channelneuromodulationorphan receptorsregulator of G protein signaling (RGS)regulator of G protein signaling 7 (RGS7)stress

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