Related Experiment Video
Updated: Jul 20, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Massive Thymic Hyperplasia Mimicking Anterior Mediastinal Neoplasia in Occult Graves' Disease
Christopher James Kennedy1, David James William Paton2
1Department of Cardiothoracic Anaesthetics, Fiona Stanley Hospital, Perth, Western Australia, Australia.
Abstract:
Background Thymic hyperplasia is a recognized complication of Graves' disease that can present radiologically as an anterior mediastinal mass. Case Description We present a unique case of massive thymic hyperplasia occurring in a 24-year-old female without a known history of thyroid or other systemic disease in whom Graves' disease first manifested intraoperatively during thymectomy for presumed neoplasia. Conclusion We suggest that the work-up of all anterior mediastinal masses should include a comprehensive search for medical causes of reversible thymic enlargement.
Related Concept Videos
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Hyperthyroidism I: Introduction
Hyperthyroidism II: Pathophysiology
Graves' Disease I: Introduction
Graves Disease II: Pathophysiology
Goiter

