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Malonyl CoA Decarboxylase Inhibition Improves Cardiac Function Post-Myocardial Infarction

Wei Wang1,2, Liyan Zhang1, Pavan K Battiprolu3

  • 1Cardiovascular Research Centre, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

JACC. Basic to Translational Science
|July 18, 2019
PubMed

Keywords:
ATGL, adipose triglyceride lipaseCPT1, carnitine palmitoyltransferase 1EF, ejection fractionFOXO3, forkhead box O3MCD, malonyl coenzyme A decarboxylaseMI, myocardial infarctionSERCA2, sarco(endo)plasmic reticulum Ca2+-ATPase 2SOD, superoxide dismutaseSPT, serine palmitoyltransferaseTAG, triacylglycerolTrx, thioredoxinfatty acid oxidationglucose oxidationheart failureuncoupling of glycolysis

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