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Rosette-forming glioneuronal tumor: an update
C T Anyanwu1,2, T M Robinson3, J H Huang4,3
1Texas A&M Health Science Center College of Medicine, 8447 State Highway 47, Bryan, TX, 77807, USA. chi2ag@yahoo.com.
Rosette-forming glioneuronal tumors (RGNTs) are rare, benign nervous system neoplasms. Comprehensive review of recent literature characterizes their symptoms, imaging, treatment, and prognosis, aiding clinical understanding.
Area of Science:
- Neurology
- Neuro-oncology
- Pathology
Background:
- Rosette-forming glioneuronal tumor (RGNT) is a rare primary nervous system neoplasm.
- Existing literature is sparse, with limited case reports and outdated reviews.
Purpose of the Study:
- To provide a comprehensive review of recent literature on RGNTs.
- To characterize presenting symptoms, radiological findings, treatment strategies, and prognosis.
Main Methods:
- Medline search for case reports of primary RGNTs.
- Synthesis of recent literature to consolidate key characteristics.
Main Results:
- RGNTs are benign, indolent tumors with glial and neurocytic components.
- Common symptoms include headaches and visual disturbances; frequent locations are the fourth ventricle and cerebellum.
- Surgical gross total resection (GTR) is associated with a better prognosis.
Conclusions:
- RGNTs are rare tumors requiring updated characterization.
- Timely diagnosis and surgical management, particularly GTR, are crucial for favorable outcomes.
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