A comparison of Icare PRO and Perkins tonometers in anesthetized children

Massimiliano Serafino1, Edoardo Villani1, Andrea Lembo2

  • 1Department of Clinical Sciences and Community Health, Eye Clinic San Giuseppe Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Multimedica, University of Milan, Via San Vittore, 12, 20123, Milan, Italy.

Insights

The Perkins applanation tonometer (PAT) shows higher reliability for measuring intraocular pressure (IOP) in children compared to the Icare PRO (ICP). Both devices demonstrated a significant correlation between IOP and central corneal thickness (CCT).

Area of Science:

  • Ophthalmology
  • Pediatric Eye Care
  • Ophthalmic Instrumentation

Background:

  • Accurate intraocular pressure (IOP) measurement is critical in pediatric ophthalmology, particularly in aphakic or strabismus patients.
  • Existing tonometers may have limitations in accuracy and reliability in pediatric populations.
  • Central corneal thickness (CCT) is a known factor influencing IOP readings.

Purpose of the Study:

  • To compare IOP measurements between the Perkins applanation tonometer (PAT) and Icare PRO (ICP) in anesthetized children.
  • To evaluate intra-operator and inter-operator reliability for both tonometer devices.
  • To assess the influence of central corneal thickness (CCT) on IOP measurements obtained by PAT and ICP.

Main Methods:

  • Seventy children undergoing examination under anesthesia were included.
  • IOP was measured twice with PAT and ICP by two operators on each eye.
  • Central corneal thickness (CCT) was measured using ultrasound pachymetry; Bland-Altman analyses and intraclass correlation coefficients (ICC) were used for evaluation.

Main Results:

  • The Icare PRO (ICP) tended to overestimate IOP compared to the Perkins applanation tonometer (PAT), with a mean difference of 1.97 mmHg.
  • Repeatability and reproducibility were higher for PAT (repeatability 0.96, reproducibility 0.76) than for ICP (repeatability 0.81, reproducibility 0.70).
  • A significant correlation (r=0.66) was found between IOP and CCT for both instruments.

Conclusions:

  • The Perkins applanation tonometer (PAT) demonstrates superior repeatability and reproducibility for IOP measurements in pediatric patients compared to the Icare PRO (ICP).
  • ICP tends to overestimate IOP relative to PAT in this cohort.
  • Both tonometers showed a significant correlation with central corneal thickness (CCT), highlighting its importance in IOP assessment.
Abstract

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