Visual Performance and High-Order Aberrations with Different Contact Lens Prototypes with Potential for Myopia...

Area of Science:

• Ophthalmology
• Optometry
• Vision Science

Background:

• Myopia control contact lenses (CLs) utilize variable power designs that may induce higher-order aberrations (HOA).
• Evaluating image quality and visual performance is crucial before clinical trials for new myopia control CLs.

Purpose of the Study:

• To assess retinal image quality and visual performance in three novel multifocal CL prototypes for myopia control.
• To compare the effects of different CL designs on higher-order aberrations, visual acuity, and contrast sensitivity.

Main Methods:

• A double-blind, cross-over study involving 30 myopic subjects wearing three multifocal CLs and one monofocal control lens.
• Measurements included higher-order aberrations (HOA), glare (halo), high- and low-contrast visual acuity (VA), and contrast sensitivity function (CSF).

Main Results:

• All tested CLs significantly increased HOA and halo size compared to the control lens.
• Low-contrast visual acuity was significantly reduced with two of the test lenses (Lens 1 and Lens 2).
• Lens 1, with a radial refractive gradient, showed the largest increase in HOA and halo size.

Conclusions:

• Myopia control CLs with variable power designs can degrade retinal image quality and visual performance.
• Contact lenses featuring larger stabilized areas for distance vision appear to minimize visual interference and HOA induction.