Related Experiment Video
Updated: Jan 22, 2026

Author Spotlight: Advances in Evaluating Human Lung Epithelial Cells' Response to Metal-Organic Frameworks
Published on: May 26, 2023
Formation of Metal-Organic Frameworks on a Metal Ion-Doped Polymer Substrate: In-Depth Time-Course Analysis Using
Takaaki Tsuruoka1, Manami Hata1, Shoya Hirao1
1Department of Nanobiochemistry, Frontiers of Innovative Research in Science and Technology (FIRST) , Konan University , 7-1-20 Minatojimaminami , Chuo-ku, Kobe 650-0047 , Japan.
Abstract:
The growth of metal-organic frameworks (MOFs) on a metal ion-doped polymer as a precursor and support substrate was investigated based on mechanistic and kinetic analyses. The studies were performed by varying the reaction temperature and the concentrations of the organic ligand and nucleation-promoted additive. Using the NH2-MIL-53(Al) framework as a model system, a systematic study of the mechanism of formation of tetragonal- and rod-shaped NH2-MIL-53(Al) crystals on the substrate was performed. The nucleation rate in the early stage of the reaction is a major factor in determining the surface morphology of the resultant NH2-MIL-53(Al) crystal films, as confirmed by changing the concentration of organic ligands and by employing pyridine additives. These results provide a fundamental understanding of the influence of the nucleation rate on the ability to control the morphology and structure of MOF crystal films.
Related Concept Videos
Bonding in Metals
Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
Alkali Metals
Table 1: Properties of the alkali metals
Formation of Complex Ions
Metallic Solids
All metallic solids exhibit high thermal and electrical conductivity, metallic luster, and malleability....
Properties of Transition Metals

