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A frequency distribution table can be constructed using the steps given below.
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Related Experiment Video

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Fabrication of Myogenic Engineered Tissue Constructs
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In Vivo Tracking of Tissue Engineered Constructs.

Carmen J Gil1, Martin L Tomov1, Andrea S Theus1

  • 1Wallace H. Coulter Department of Biomedical Engineering, Emory University School of Medicine and Georgia Institute of Technology, Atlanta, GA 30322, USA.

Micromachines
|July 19, 2019
PubMed
Summary

Advanced imaging techniques are crucial for tracking 3D bioprinted tissue constructs in regenerative medicine. Developing non-toxic, high-resolution in vivo methods is key for successful bioartificial tissue development.

Keywords:
3D bioprintingadditive manufacturingbioluminescencecomputed tomography (CT)fluorescence spectroscopyin vivo imagingmagnetic resonant imaging (MRI)magnetic-particle imagingmultimodal imagingoptical coherence tomographyphotoacoustic imagingscaffold trackingtissue engineeringultrasound

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Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Biomaterials and tissue engineering offer promise for bioartificial tissues and organs.
  • Additive biomanufacturing and 3D bioprinting enable complex, patient-specific tissue constructs.
  • In vivo visualization of engineered tissues is essential for regenerative medicine advancement.

Purpose of the Study:

  • To review current imaging techniques for tracking tissue engineering scaffolds in vivo.
  • To highlight methods suitable for 3D bioprinted tissue constructs.
  • To emphasize the need for adequate spatial/temporal resolution and penetration depth.

Main Methods:

  • Review of existing literature on in vivo imaging modalities.
  • Focus on techniques applicable to tissue engineering scaffolds.
  • Consideration of 3D bioprinted constructs.

Main Results:

  • Various imaging techniques are employed in research and clinical settings.
  • Key requirements include minimal toxicity, disruption, and destruction.
  • Adequate signal-to-noise ratios are necessary for clinical relevance.

Conclusions:

  • Effective in vivo tracking of bioengineered tissues requires advanced imaging.
  • The development of non-invasive, high-performance imaging modalities is critical.
  • Continued research is needed to optimize techniques for 3D bioprinted constructs.