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Updated: Jan 22, 2026

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis
Published on: June 10, 2022
[Diagnostic accuracy of ROMA index in diagnosing ovarian malignancy in pelvic mass patients]
1Department of Obstetrics and Gynecology, Zhujiang Hospital of Southern Medical University, Guangzhou 510280, China.
Abstract:
Objective: To evaluate ROMA in assessing malignancy risk of pelvic mass with Meta-analysis. Methods: PubMed, ISI Web of Science, and Cochrane literature were searched until December 2017. Combine and analyse sensitivity, specificity, positive likelihoodratio, negative likelihood ratio, diagonistic odd ratio and AUC. Results: Data of ROMA was retrieved from 8 studies, sensitivity and specificity were 86% and 77% respectively, and AUC was 0.899. Conclusion: According to Meta analysis of previous studies, sensitivity and specificity of ROMA are high enough to be used as an index in setting of ovarian cancer diagnosis.
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