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Updated: Jan 22, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
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Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

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[Prognosis of bronchopulmonary dysplasia in preterm infants: a follow-up during infancy]

Hong-Ling Wei1, Yan Xing, Hui Wu

  • 1Department of Pediatrics, Peking University Third Hospital, Beijing 100191, China. xingyan770424@vip.sina.com.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics
|July 19, 2019
PubMed

Insights

Infants with bronchopulmonary dysplasia (BPD) experience slower growth and delayed motor development. They are also more prone to respiratory illnesses like pneumonia and wheezing during infancy.

Area of Science:

  • Neonatology
  • Pediatric Pulmonology
  • Developmental Pediatrics

Background:

  • Bronchopulmonary dysplasia (BPD) is a chronic lung disease affecting preterm infants.
  • BPD can impact long-term physical and neurodevelopmental outcomes.
  • Understanding these impacts is crucial for comprehensive infant care.

Purpose of the Study:

  • To assess physical development in infants with BPD.
  • To determine the incidence of common respiratory diseases in BPD infants.
  • To evaluate motor development trajectories in infants with BPD.

Main Methods:

  • Retrospective analysis of clinical data from preterm infants with and without BPD.
  • Comparison of physical growth, respiratory illness incidence, and motor development.
  • Data collected from infants admitted between January 2012 and December 2015.

Main Results:

  • BPD infants showed higher rates of extrauterine growth retardation and readmissions for respiratory infections.
  • Significantly smaller head circumference was observed in BPD infants at 3, 6, and 12 months.
  • Delayed gross, fine, and overall motor development noted at 6 and 9 months in BPD infants.

Conclusions:

  • Infants with BPD are at increased risk for growth deficits and respiratory complications.
  • Slower head circumference growth and delayed motor milestones are characteristic of BPD.
  • Early identification and intervention are vital for managing BPD-related developmental challenges.
Abstract

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