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Subacute/chronic type A aortic dissection: a retrospective cohort study.

Jinlin Wu1,2, Enzehua Xie1, Juntao Qiu1

  • 1Department of Cardiovascular Surgery, Fuwai Hospital, Peking Union Medical College, Beijing, China.

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|July 19, 2019
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Subacute/chronic type A aortic dissection (TAAD) presents differently and has better survival rates than acute TAAD. Surgical strategies for acute TAAD are effective for subacute/chronic cases, yielding excellent outcomes.

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Area of Science:

  • Cardiovascular Surgery
  • Thoracic Surgery
  • Aortic Diseases

Background:

  • Type A aortic dissection (TAAD) is a life-threatening condition requiring timely intervention.
  • Distinguishing between acute and subacute/chronic TAAD is crucial for treatment planning and prognosis.
  • Limited data exists on the specific clinical characteristics and outcomes of subacute/chronic TAAD.

Purpose of the Study:

  • To delineate the clinical presentations of subacute/chronic TAAD.
  • To compare the surgical treatment and outcomes of subacute/chronic TAAD versus acute TAAD.
  • To evaluate the applicability of current surgical strategies for acute TAAD to subacute/chronic TAAD.

Main Methods:

  • Retrospective analysis of 1092 patients with TAAD.
  • Classification into subacute/chronic (181 patients) and acute (911 patients) TAAD groups.
  • Propensity score matching to compare early and late outcomes between groups.

Main Results:

  • Subacute/chronic TAAD patients commonly presented with chest tightness, mild pain, and sweating, unlike the intense pain typical of acute TAAD.
  • Subacute/chronic TAAD demonstrated significantly better early and late survival rates compared to acute TAAD (6.1% vs 11.6% early mortality).
  • Survival rates at 1, 3, and 5 years were higher for subacute/chronic TAAD, confirmed by propensity score matching.

Conclusions:

  • Subacute/chronic TAAD exhibits distinct clinical features compared to acute TAAD.
  • Patients with subacute/chronic TAAD experience superior early and late survival outcomes.
  • Standard surgical approaches for acute TAAD are effective and yield excellent results for subacute/chronic TAAD.