Related Experiment Video
Updated: Jan 22, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Energy Conservation Management for People With Multiple Sclerosis-Related Fatigue: Who Benefits?
Lyan J M Blikman1, Jetty van Meeteren2, Jos W R Twisk3
1Lyan J. M. Blikman, PhD, is Job Coordinator, Research Support, Twente University, Enschede, the Netherlands. At the time of this study, she was PhD Student, Department of Rehabilitation Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
Objective:
We investigated whether demographic, disease-related, or personal baseline determinants can predict a positive response to energy conservation management (ECM).
Method:
We conducted a secondary analysis of a single-blind, two-parallel-arms randomized controlled trial that included ambulatory adults with severe MS-related fatigue. Therapy responders and nonresponders were categorized by Checklist Individual Strength fatigue change scores between baseline and end of treatment. Logistic regression analyses were used to assess the determinants of response.
Results:
Sixty-nine participants were included (ECM group, n = 34; control group, n = 35). In the ECM group, fatigue severity, perception of fatigue, illness cognitions about MS, and social support discrepancies were related to the probability of being a responder.
Conclusion:
The results suggest that people with MS-related fatigue who had a less negative perception of fatigue and who perceived fewer disease benefits and a higher discrepancy in social support had the best response to ECM treatment.
Related Concept Videos
Conservation of Energy
Conservation of Mechanical Energy
When a...
Conservation of Energy: Application
Energy Conservation and Bernoulli's Equation
All the terms in the equation have the dimension of energy per unit volume. The kinetic energy per unit volume is called the kinetic energy density, and the potential energy per unit volume is...
Conservation of Energy in Control Volume
For steady flow systems, the time derivative of the stored energy becomes zero since there is no energy accumulation within the control volume. This simplifies the energy equation to:
What is Energy?

