Related Experiment Video For CEA
Updated: Jan 22, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Elevation of Serum CEA in Patients with Squamous Cell Carcinoma of the Anus
Gabriel T Raab1, Daniel S O'Neil2, Ravi P Kiran1,3,4
1Department of Epidemiology, Mailman School of Public Health, Columbia University , New York , New York , USA.
Abstract:
The proportion of anal cancer cases that produce elevated carcinoembryonic antigen (CEA) levels is not well described in the medical literature. In this study, we used electronic health record data from a single urban cancer center to identify patients from 2004-2018 with anal cancer who have also had a pre-initial treatment CEA measurement. We identified 40 patients who met our eligibility criteria. Of those, 11 (27.5%) had an elevated pretreatment CEA. Elevated CEA was not associated with any of the clinical or demographic covariates; however, three out of five patients with a recurrence had an elevated CEA.
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