Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

1.1K
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.1K
Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

29.2K

Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
29.2K
Sample Preparation for Analysis: Advanced Techniques01:08

Sample Preparation for Analysis: Advanced Techniques

1.3K
Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
1.3K
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

492
Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
492
Base Excision Repair01:54

Base Excision Repair

26.1K
One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
The first step of...
26.1K
Lewis Acids and Bases02:33

Lewis Acids and Bases

48.2K
In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
48.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the Therapeutic Potential of Ganoderic Acid A Against Inflammatory Bowel Disease Based on Network Pharmacology, Molecular Docking, and Intestinal Organoid Validation.

International journal of molecular sciences·2026
Same author

Squid-ink-derived eumelanin nanoparticles improve glycaemic control through gut-centered metabolic remodeling in type 2 diabetes.

International journal of biological macromolecules·2026
Same author

Preparation of chitin derived oligosaccharide monomers, evaluation of in vitro hypoglycemic activity and investigation of potential mechanisms.

Carbohydrate research·2026
Same author

A quantum multi-sensor data fusion self-supervised learning framework for IIoT anomaly detection.

Scientific reports·2026
Same author

A melanin-chitin complex from the shell of <i>Mytilus edulis</i>: structural characterization and evidence for possible intermolecular interactions.

Journal of materials chemistry. B·2026
Same author

An ultrasensitive double-antigen sandwich time-resolved fluorescent immunochromatographic assay for quantification of Brucella antibodies.

Mikrochimica acta·2026

Related Experiment Video

Updated: Jan 22, 2026

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids
07:14

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids

Published on: May 16, 2025

638

Advances in chitosan-based nanoparticles for oncotherapy.

Enhui Zhang1, Ronge Xing1, Song Liu1

  • 1Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China; Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, No. 1 Wenhai Road, Qingdao 266237, China.

Carbohydrate Polymers
|July 20, 2019
PubMed
Summary

Chitosan nanoparticles are promising for cancer therapy due to their biocompatibility and targeted delivery of anti-tumor agents. This review explores their structure-function relationships and future potential in oncotherapy.

Keywords:
Anti-tumorChitosanDrug deliveryNanoparticle

More Related Videos

Author Spotlight: Advancing Gene Silencing Research in Silkworms with dsRNA Delivery Through Feeding Chitosan Nanoparticles
05:36

Author Spotlight: Advancing Gene Silencing Research in Silkworms with dsRNA Delivery Through Feeding Chitosan Nanoparticles

Published on: October 4, 2024

2.6K
Preparation and Characterization of SDF-1&#945;-Chitosan-Dextran Sulfate Nanoparticles
12:00

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles

Published on: January 22, 2015

12.9K

Related Experiment Videos

Last Updated: Jan 22, 2026

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids
07:14

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids

Published on: May 16, 2025

638
Author Spotlight: Advancing Gene Silencing Research in Silkworms with dsRNA Delivery Through Feeding Chitosan Nanoparticles
05:36

Author Spotlight: Advancing Gene Silencing Research in Silkworms with dsRNA Delivery Through Feeding Chitosan Nanoparticles

Published on: October 4, 2024

2.6K
Preparation and Characterization of SDF-1&#945;-Chitosan-Dextran Sulfate Nanoparticles
12:00

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles

Published on: January 22, 2015

12.9K

Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Oncology

Background:

  • Chitosan is a biocompatible and biodegradable material.
  • Chitosan nanoparticles offer simple preparation techniques for drug delivery.
  • These nanoparticles are investigated as carriers for various anti-tumor agents.

Purpose of the Study:

  • To review factors influencing the anti-tumor efficacy of chitosan-based nanoparticles.
  • To explore the function-structure relationship of these nanoparticles.
  • To highlight recent advancements in chitosan-based nanoparticles for cancer treatment.

Main Methods:

  • Literature review of recent studies on chitosan-based nanoparticles for oncotherapy.
  • Analysis of nanoparticle structures, properties, and pharmacological effects.
  • Discussion of targeting mechanisms (passive and active) for drug delivery.

Main Results:

  • Chitosan nanoparticles can deliver diverse anti-cancer agents (chemotherapeutics, nucleic acids, proteins, photosensitizers).
  • Factors affecting anti-tumor efficacy are summarized, aiding function-structure relationship exploration.
  • Recent studies demonstrate the potential of these nanoparticles in various oncotherapy strategies.

Conclusions:

  • Chitosan-based nanoparticles show significant promise as drug carriers in cancer therapy.
  • Understanding structure-property relationships is crucial for optimizing anti-tumor efficacy.
  • Future research should address challenges and explore further development in this field.