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Updated: Jan 22, 2026

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation
08:10

Estimating Bilateral Atrial Function by Cardiovascular Magnetic Resonance Feature Tracking in Patients with Paroxysmal Atrial Fibrillation

Published on: July 20, 2022

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Transmitral inflow wave and progression from paroxysmal to permanent atrial fibrillation in Asian people

Takashi Nakagawa1,2, Hisao Hara1, Masaya Yamamoto1

  • 1Department of Cardiology, National Center for Global Health and Medicine, Tokyo, Japan.

Heart Asia
|July 20, 2019
PubMed

Insights

Lower peak A velocity in transmitral inflow waves can predict the progression of paroxysmal atrial fibrillation to permanent atrial fibrillation. This finding may aid in early intervention for patients at risk.

Area of Science:

  • Cardiology
  • Echocardiography
  • Atrial Fibrillation Research

Background:

  • Paroxysmal atrial fibrillation (PAF) can advance to permanent atrial fibrillation (AF).
  • Predictive markers for PAF progression are crucial for timely clinical management.
  • The role of transmitral inflow waves in predicting this progression remains unclear.

Purpose of the Study:

  • To investigate the association between transmitral inflow waves and the progression of PAF to permanent AF.
  • To determine if specific echocardiographic parameters can predict AF progression.

Main Methods:

  • Retrospective analysis of clinical and echocardiographic data from 88 patients with PAF.
  • Exclusion of patients with structural heart disease, significant valvular disease, cardiomyopathy, cardiac device, or LVEF <50%.

Main Results:

  • Patients who progressed to permanent AF were more likely to be male.
  • Lower peak A velocity was observed in patients progressing to permanent AF.
  • After covariate adjustment, lower peak A velocity independently predicted progression to permanent AF (p=0.025).

Conclusions:

  • Peak A velocity of transmitral inflow waves may serve as a useful predictor for PAF progression.
  • This finding is particularly relevant for predicting progression in Asian populations.
  • Echocardiographic assessment of transmitral inflow waves could enhance risk stratification for AF progression.
Abstract

Keywords:
echocardiographyparoxysmal atrial fibrillationprogressiontransmitral inflow wave

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