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Related Concept Videos

Light as Energy01:35

Light as Energy

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The energy required to carry out photosynthesis is light— typically electromagnetic radiation from the sun. The range of all possible wavelengths is known as the electromagnetic spectrum.
Photons
A photon is a discrete electromagnetic particle or bundle of energy. Photons are characterized by their frequency, wavelength, and amplitude, similar to the properties of a wave. Waves with higher frequencies transmit more energy and have shorter wavelengths than longer wavelengths that transmit...
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The universe is composed of matter in different forms, and all forms of matter contain energy.  The different forms of energy on Earth originate from the Sun — the ultimate energy source. Plants capture light energy from the Sun, and, via the process of photosynthesis, convert it into chemical energy. This stored energy from plants can be harnessed in many ways. For example, eating plant products as food provides energy for our body to function, and burning wood or coal (fossilized...
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The free energy change for a process taking place with reactants and products present under nonstandard conditions (pressures other than 1 bar; concentrations other than 1 M) is related to the standard free energy change according to this equation:
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Free energy—abbreviated as G for the scientist Gibbs who discovered it—is a measurement of useful energy that can be extracted from a reaction to do work. It is the energy in a chemical reaction that is available after entropy is accounted for. Reactions that take in energy are considered endergonic and reactions that release energy are exergonic. Plants carry out endergonic reactions by taking in sunlight and carbon dioxide to produce glucose and oxygen. Animals, in turn, break...
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Activation Energy01:26

Activation Energy

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Activation energy is the minimum amount of energy necessary for a chemical reaction to move forward. The higher the activation energy, the slower the rate of the reaction. However, adding heat to the reaction will increase the rate, since it causes molecules to move faster and increase the likelihood that molecules will collide. The collision and breaking of bonds represents the uphill phase of a reaction and generates the transition state. The transition state is an unstable high-energy state...
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Related Experiment Video

Updated: Jan 22, 2026

Isolation of Papillary and Reticular Fibroblasts from Human Skin by Fluorescence-activated Cell Sorting
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FLUORESCENT LIGHT ENERGY: The Future for Treating Inflammatory Skin Conditions?

Deirdre Edge1,2,3,4, Maiken Mellergaard1,2,3,4, Carsten Dam-Hansen1,2,3,4

  • 1Drs. Edge, Mellergaard, and Nielsen are with the Department of Research and Development at FB Dermatology, Ltd. in Ballerup, Denmark. Mellergaardis also with IVH, Immunology at the University of Copenhagen in Frederiksberg, Denmark.

The Journal of Clinical and Aesthetic Dermatology
|July 20, 2019
PubMed
Summary

Fluorescent light energy (FLE) enhances skin repair by boosting collagen production and reducing inflammation. This novel photobiomodulation approach improves skin texture and promotes healing for various skin conditions.

Keywords:
AcneFLELEDaestheticangiogenesisanti-inflammatorybiophotonicschromophorecollagencytokinesfibroblastsfluorescent light energyinflammatory skin conditionsmacrophagesphotobiomodulationrejuvenationtherapeutic

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Area of Science:

  • Biophotonics
  • Dermatology
  • Cellular Biology

Background:

  • Novel photobiomodulation using fluorescent light energy (FLE) shows clinical efficacy in skin conditions.
  • The underlying cellular mechanisms of FLE's action require elucidation.

Purpose of the Study:

  • To investigate the cellular mechanisms of FLE on skin and immune cells.
  • To assess FLE's impact on collagen production, inflammation, and angiogenesis.

Main Methods:

  • Clinical observation of FLE on acne vulgaris.
  • In vitro assessment of FLE's effect on human dermal fibroblasts (HDFs) and keratinocytes (HEKs).
  • Evaluation of FLE's impact on angiogenesis in human aortic endothelial (HAE) cells.

Main Results:

  • FLE reduced acne lesions and redness, improving skin texture.
  • FLE enhanced collagen production in HDFs and modulated inflammatory cytokine profiles in HDFs and HEKs.
  • FLE promoted angiogenesis in HAE cells.

Conclusions:

  • FLE demonstrates potential in enhancing collagen synthesis, modulating skin inflammation, and promoting angiogenesis.
  • Findings suggest FLE as a promising therapeutic for inflammatory skin conditions and aesthetic applications.