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Non-typhoidal Salmonella aortitis.

Giulia Gardini1, Paola Zanotti2, Alessandro Pucci3

  • 1Department of Infectious and Tropical Diseases, ASST Spedali Civili and University of Brescia, Brescia, Italy. giulia.gardini90@gmail.com.

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|July 20, 2019
PubMed
Summary
This summary is machine-generated.

Non-typhoidal Salmonella (NTS) causes infective aortitis, a serious condition. This case highlights Salmonella Enteritidis causing abdominal aortitis in an elderly male, requiring medical and surgical care.

Keywords:
AortitisExtra-intestinal localization by SalmonellaSalmonella

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Area of Science:

  • Infectious Diseases
  • Cardiovascular Medicine
  • Microbiology

Background:

  • Non-typhoidal Salmonella (NTS) is a significant cause of infective aortitis, associated with high morbidity and mortality.
  • NTS infections typically result from fecal-oral transmission via contaminated food, water, or direct contact.
  • Bacteremia occurs in about 5% of NTS gastroenteritis cases, with a 40% incidence of extra-intestinal focal infections.

Observation:

  • This report details a case of abdominal sub-renal aortitis.
  • The causative agent identified was Salmonella enterica serovar Enteritidis.
  • The patient was an 80-year-old male.

Findings:

  • NTS spp. account for approximately 40% of all infective aortitis cases.
  • Extra-intestinal focal infections in NTS bacteremia can arise from hematogenous spread, direct extension, or inoculation.
  • Successful management of infective aortitis necessitates combined medical and surgical interventions.

Implications:

  • This case underscores the importance of considering NTS in the differential diagnosis of infective aortitis, particularly in elderly patients.
  • Prompt diagnosis and aggressive treatment, including antibiotics and surgical repair, are crucial for favorable outcomes.
  • Further research into NTS pathogenesis and treatment strategies for infective aortitis is warranted.