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Updated: Jan 22, 2026

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
[Heterogeneity amongst different diagnostic tools in frailty screening]
M J Redín-Sagredo1, P Aldaz Herce, A Casas Herrero
1Centro de Salud de San Juan. Servicio Navarro de Salud. Pamplona.. mj.redsag@gmail.com.
Frailty prevalence varied significantly by diagnostic tool in older adults. The Timed Up-to-Go (TUG) and Gait Speed (GS) tests are recommended for early frailty detection in Primary Health Care settings.
Area of Science:
- Gerontology
- Primary Health Care
- Clinical Diagnostics
Background:
- Frailty is a state of vulnerability linked to aging and functional decline, necessitating early detection.
- Primary Health Care (PHC) is crucial for frailty management, but lacks a gold standard diagnostic tool.
- This study addresses the need for effective frailty detection within PHC.
Purpose of the Study:
- To analyze the prevalence of frailty in a Primary Health Care population.
- To identify the most effective diagnostic tool for frailty detection in PHC.
- To evaluate the utility of Fried phenotype, SPPB, TUG, and GS tests.
Main Methods:
- A cross-sectional study involving 225 individuals over 75 years old from Navarre.
- Four frailty diagnostic tests were administered: Fried phenotype, SPPB, TUG, and GS.
- Exclusion criteria included inability to complete any test.
Main Results:
- Frailty prevalence varied widely: 8.3% (Fried), 13.7% (SPPB), 46.2% (TUG), and 52.2% (GS).
- Participants had a mean age of 80.5 years, with 80% on polypharmacy and 8.4% cognitive impairment.
- Independence levels were 31.1% for basic ADLs and 41.3% for instrumental ADLs.
Conclusions:
- Significant heterogeneity in frailty prevalence was observed based on the diagnostic tool used.
- The Timed Up-to-Go (TUG) and Gait Speed (GS) tests are proposed as reliable, rapid, and simple early predictors of frailty in PHC.
- These findings support the use of TUG and GS for early frailty detection in Primary Health Care settings.
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