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Related Experiment Videos

Peptide containing vesicles within neuro-neuronal synapses.

G Sterba, G Hoheisel, R Wegelin

    Brain Research
    |June 15, 1979
    PubMed
    Summary
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    The neurosecretory system

    Area of Science:

    • Neuroscience
    • Cell Biology
    • Neuroendocrinology

    Background:

    • The classical neurosecretory system involves axon terminals that interact with surrounding cells.
    • Understanding the structural differences in axon terminals is crucial for comprehending neuroendocrine regulation.

    Purpose of the Study:

    • To differentiate the morphology of axon terminals in the descending and ascending parts of the neurosecretory system.
    • To identify specific features of neuro-neuronal synapses within the ascending neurosecretory tract.

    Main Methods:

    • Morphological analysis of axon terminals in the neurosecretory system.
    • Electron microscopy to examine synaptic structures and vesicle presence.

    Main Results:

    Related Experiment Videos

  • Axon terminals in the descending part are undifferentiated or form synaptoids/synapses with pituicytes and glandular cells.
  • Axon terminals in the ascending part exhibit characteristics of true presynaptic elements, forming synapses with other neurons.
  • Neurophysin vesicles are a distinctive feature of these neuro-neuronal synapses.

    • Conclusions:

    • The ascending part of the neurosecretory system features true neuro-neuronal synapses.
    • The presence of neurophysin vesicles characterizes these specific neuro-neuronal connections, differentiating them from neuro-glandular interactions.