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Updated: Jan 22, 2026

Ultrasound-guided Transthoracic Intramyocardial Injection in Mice
Published on: August 5, 2014
Two-Dimensional Laser-Align Device for Ultrasound-Guided Injection
Eric Chiwei Shiao1, Po-Ling Kuo2,3
1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei 10617, Taiwan.
Abstract:
Ultrasound-guided injection is a widely used technique, however, it takes substantial amounts of time for novices to master the skill. The most critical issue to improve the accuracy of the injection is to align the needle with the scan plane of the ultrasound beam and orient the needle angle after piercing skin to aim at the targeted tissue. In the present study, we developed a two-dimensional laser align device to assist physicians to accurately position the needle in the scan plane and advance it at an angle correctly pointing to the target. The device is inexpensive, light-weighted, and easy to fabricate and accommodate for any types of ultrasound probe. Statistical analysis revealed that the assistance with our device significantly reduced the successful targeting time and times of retargeting in comparison with the traditional freehand approach or only with in-plane assistance for inexperience subjects. Our results indicate that the device exhibits great potential in effectively reducing the learning time to master the skill and speeding up the procedure for ultrasound-guided injection.
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