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Updated: Jan 22, 2026

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
Published on: August 14, 2017
von Willebrand Factor: A Tool to Predict Severity and Prognosis in Liver Disease
Mayank Jain1, Joy Vargese1, Deepti Sachan1
1Consultant, Institute of Liver Disease and Transplantation, Gleneagles Global Health City,Chennai, Tami Nadu.
Abstract:
Von Willebrand factor (vWF) is an adhesive and multimeric glycoprotein that has a central role in primary hemostasis. v W F levels correlate with thrombosis risk and inversely with bleeding risk within the apparently healthy population. Recently, numerous publications in Indian and western literature have focussed to its role in liver diseases like acute liver failure, chronic liver disease, non cirrhotic portal hypertension and tropical infections eg. dengue. The present review encapsulates the recent advances in this aspect.
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