Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chromosome Replication02:31

Chromosome Replication

10.5K
Before a cell can divide, it must accurately replicate all of its chromosomes, including the DNA and its associated histone and non-histone proteins.  This process begins at numerous origins of replication during the S phase of the cell cycle in each of a cell’s chromosomes simultaneously. Certain nucleotides can act as origins of replication, but these sequences are not well defined - especially in complex, multi-cellular, eukaryotic species. The length of DNA that spans an origin...
10.5K
Replication in Eukaryotes02:31

Replication in Eukaryotes

203.8K
Overview
203.8K
Replication in Prokaryotes02:35

Replication in Prokaryotes

97.2K
Overview
97.2K
DNA Replication02:40

DNA Replication

58.8K
DNA replication involves the separation of the two strands of the double helix, with each strand serving as a template from which the new complementary strand is copied.  After replication, each double-stranded DNA includes one parental or “old” strand and one “new” strand. This is known as semiconservative replication. The resulting DNA molecules have the same sequence and are divided equally into the two daughter cells.
Replication in Prokaryotes
DNA replication...
58.8K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.0K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.0K
Genomics02:02

Genomics

39.8K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
39.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clarifying the scope and capabilities of ROTS in differential expression analysis.

Bioinformatics (Oxford, England)·2026
Same author

Joint modeling of longitudinal and time-to-event data for dynamic disease risk prediction using proteomics.

Protein science : a publication of the Protein Society·2026
Same author

REACTOR: REgulon Activity analysis and Comparison Tool for single-cell transcriptOmics Research.

Bioinformatics (Oxford, England)·2026
Same author

Therapeutic TG2 inhibition reverses systemic multiomic dysregulation in celiac disease.

BMC medicine·2026
Same author

Testosterone Exposure During Fetal Masculinization Programming Window Determines the Kidney Size in Adult Mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Complete Data Analysis Workflow for Quantitative DIA Mass Spectrometry Using Nextflow.

Journal of proteome research·2026
Same journal

Phenotypical and functional characterization of a HepG2 cell clone stably overexpressing cytochrome P450 (CYP) 2C9.

BMC research notes·2026
Same journal

Inefficacy of a novel osmotic associative learning assay in C. elegans.

BMC research notes·2026
Same journal

Anticancer proteasome inhibitors are detrimental to the growth of Toxoplasma gondii in vitro.

BMC research notes·2026
Same journal

Body mass index, nutritional knowledge, and eating attitudes in dancer and non-dancer students.

BMC research notes·2026
Same journal

Using LLM-generated tools to extract information about reporting statistical software in biomedical and health science research articles.

BMC research notes·2026
Same journal

Comparative hemostatic efficacy of oxidized regenerated cellulose powder and fibrin glue in a rat model of induced liver parenchymal hemorrhage.

BMC research notes·2026
See all related articles

Related Experiment Video

Updated: Jan 22, 2026

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome
06:40

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

Published on: March 22, 2018

6.2K

RepViz: a replicate-driven R tool for visualizing genomic regions.

Thomas Faux1, Kalle T Rytkönen2,3, Asta Laiho2

  • 1Turku Bioscience Centre, University of Turku and Åbo Akademi University, Tykistökatu 6, 20520, Turku, Finland. thmafa@utu.fi.

BMC Research Notes
|July 21, 2019
PubMed
Summary
This summary is machine-generated.

RepViz is a new R package for visualizing genomic sequencing data. It helps researchers easily compare different groups of replicates and analyze variations in sequencing counts for genomic regions.

Keywords:
Computational genomicsEpigeneticsGenome analysisVisualisation

More Related Videos

Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement
08:06

Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement

Published on: January 19, 2017

8.8K
Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
11:13

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Published on: March 12, 2020

11.6K

Related Experiment Videos

Last Updated: Jan 22, 2026

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome
06:40

G2-seq: A High Throughput Sequencing-based Technique for Identifying Late Replicating Regions of the Genome

Published on: March 22, 2018

6.2K
Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement
08:06

Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement

Published on: January 19, 2017

8.8K
Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products
11:13

Mass Spectrometry-Guided Genome Mining as a Tool to Uncover Novel Natural Products

Published on: March 12, 2020

11.6K

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • Genomic data analysis heavily relies on visualization tools.
  • Existing tools lack user-friendly methods for simultaneously viewing multiple replicate groups.
  • Efficient visualization is crucial for understanding intra- and intergroup variation in sequencing data.

Purpose of the Study:

  • To develop a user-friendly tool for visualizing genomic sequencing data across multiple replicates.
  • To enable efficient viewing of intra- and intergroup variation in sequencing counts.
  • To facilitate comparison with analysis method outputs like peak calling.

Main Methods:

  • Development of an R package named RepViz.
  • Utilizing RepViz for visualization of ChIP-seq and ATAC-seq data.
  • Demonstrating RepViz's utility in evaluating normalization, outliers, and peak calling results.

Main Results:

  • RepViz enables efficient visualization of genomic regions with multiple replicates.
  • The package aids in assessing normalization strategies and identifying outlier behavior.
  • RepViz facilitates the inspection of differential peak calling analyses and multi-data type integration.

Conclusions:

  • RepViz provides a valuable tool for replicate-driven visualization in genomic data analysis.
  • The package enhances the visual inspection of sequencing data quality and analysis outcomes.
  • RepViz is accessible via Bioconductor and Github for widespread use.