Related Experiment Video
Updated: Jan 22, 2026
Isolation of Small Noncoding RNAs from Human Serum
Published on: June 19, 2014
Serum Uric Acid Levels and Serum Lipid Levels in Patients with Ischemic Cerebrovascular Accident
Tavish Arora1, P G Mantur2, R C Bidri3
1Post Graduate, Department of Medicine, Shri B.M. Patil Medical College Hospital & Research Centre, Karnataka, Corresponding Author.
Insights
Hyperuricemia and dyslipidemia are common in acute ischemic stroke patients, particularly in females and those aged 56-70. These conditions, including low HDL cholesterol, may be significant risk factors for stroke.
Area of Science:
- Neurology
- Cardiology
- Metabolic Disorders
Background:
- Stroke is a leading cause of death globally, with increasing prevalence in the elderly population.
- Hyperuricemia and dyslipidemia are frequently observed in patients experiencing acute stroke.
- Elevated serum uric acid levels correlate with adverse lipid profiles, including decreased HDL and increased triglycerides and LDL cholesterol.
Purpose of the Study:
- To investigate the relationship between serum uric acid levels and serum lipid profiles in patients diagnosed with acute ischemic stroke.
Main Methods:
- A cross-sectional study was conducted from January 2015 to June 2016.
- Included 60 patients diagnosed with acute ischemic stroke.
- Serum uric acid and lipid levels were measured and statistically analyzed.
Main Results:
- 30% of the 60 ischemic stroke patients exhibited hyperuricemia.
- Hyperuricemia was more prevalent in females (6.2 ± 1.9) than males (5.2 ± 1.6) and predominant in the 56-70 age group.
- Dyslipidemia affected 81.7% of patients, characterized by low HDL levels (87.75%) and elevated cholesterol, triglycerides, and LDL in some cases. 15 patients had both hyperuricemia and dyslipidemia.
Conclusions:
- Hyperuricemia and associated dyslipidemia are identified as potential risk factors for acute ischemic stroke.
- The findings suggest a link between metabolic derangements and cerebrovascular events.
Background:
Stroke is a growing disease and it is the second common cause of death in the world after coronary heart disease especially in the elderly. In patients with acute stroke hyperuricemia was significantly higher than normal population with associated dyslipidemia. Hyperuricemia has been associated with decreased amount of HDL cholesterol and increased amounts of triglycerides and LDL cholesterol.
Aim:
:Serum uric acid levels and serum lipid levels in patients with ischemic cerebrovascular accident.
Material And Methods:
This was a cross-sectional study carried out between January 2015 - June 2016, which included 60 cases of acute ischemic stroke. Serum uric acid levels and serum lipid levels was done in all the patients and was statistically analyzed.
Results:
A total of 60 patients with ischemic stroke were included in the study. Out of which 43 (71.7%) were males and 17 (28.3%) were females. The mean age of the patients was 63.2 ±14.8. Mean serum uric acid levels in the patients studied was 5.5 ± 1.7, and 18 patients (30%) were hyperuricemic. Serum uric acid levels were significantly higher in females (6.2 ± 1.9) compared to the males (5.2 ±1.6). It was predominant in the age group between 56-70 years. Dyslipidemia was seen in 49 (81.7%) patients (Males were 36 and females were 13).. More than one lipid parameter was seen to be deranged in 10 male patients and 4 female patients. Of them 87.75% of patients had low HDL levels, 36.73%, 10.20% and 8.16% patient had high cholesterol, triglycerides and LDL levels respectively. The study also showed that 15 patients had both hyperuricemia and dyslipidemia.
Conclusion:
Hyperuricemia and its accompanying dyslipidemia can be considered as the risk factor for acute ischemic stroke.
Related Concept Videos
01:25Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
01:19High-Level and Low-Level Awareness
02:11Leveling Effect and Non-Aqueous Acid-Base Solutions
The Leveling Effect of a Solvent
A generic acid (HA) reacts with the generic base (B-) to yield the corresponding conjugate base (A-) and conjugate acid (HB):
01:29Leveling Effect
01:09Levels of Organization
Molecules Are Composed of Atoms, and Biomolecules Are Assembled from Molecules:
The most basic levels include atoms, molecules, and biomolecules. Atoms, the smallest unit of ordinary matter, are composed of a nucleus and electrons. Molecules...
01:18Fermi Level
At absolute zero temperature, electrons fill all energy states up to the Fermi level, leaving upper states empty. As the temperature rises,...