Related Experiment Video
Updated: Jan 22, 2026

Chronic Social Defeat Stress in Early Adolescent Male Mice
Published on: January 24, 2025
Web-Based Prescription Opioid Abuse Prevention for Adolescents: Program Development and Formative Evaluation
Sarah K Moore1, Michael Grabinski1, Sarah Bessen2
1Center for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, Lebanon, NH, United States.
This study developed Pop4Teens, a web-based program to prevent prescription opioid (PO) abuse in adolescents. Formative evaluation showed the program is potentially useful, acceptable, and increases knowledge on PO abuse prevention.
Area of Science:
- Public Health
- Adolescent Health
- Digital Health Interventions
Background:
- Nonmedical use of prescription opioids (PO) is a significant public health crisis among youth.
- Existing drug abuse prevention programs lack a specific focus on adolescent PO abuse.
- There is a need for science-based, interactive prevention tools for adolescent PO abuse.
Purpose of the Study:
- To develop and conduct a formative evaluation of Pop4Teens, a web-based program for preventing PO abuse in adolescents aged 12-17.
- To prepare for a randomized controlled trial comparing Pop4Teens with an active control website.
- To assess the impact on knowledge, attitudes, risk perceptions, and intentions regarding PO abuse.
Main Methods:
- Conducted focus groups with 30 youths across a spectrum of opioid exposure to inform program development.
- Held writing sessions with 30 youths in treatment for opioid use disorder for content development.
- Assessed feasibility and acceptability of a prototype through feedback sessions with 57 youths.
Main Results:
- Successfully developed the Pop4Teens web-based program.
- Focus group and writing session data informed program content, including quizzes and storylines.
- Feedback indicated the program is potentially useful and acceptable, with participants showing increased knowledge.
Conclusions:
- The opioid crisis necessitates effective, evidence-based prevention programs for youth.
- Pop4Teens is a promising, science-based interactive tool for preventing adolescent prescription opioid abuse.
- Further evaluation through a randomized controlled trial is warranted to confirm effectiveness.
Related Concept Videos
Cognitive Development During Adolescence
Erikson's Theory on Socioemotional Development during Adolescence
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Receptors: Overview
Prescription, Nonprescription and Orphan Drugs
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Abuse and Addiction: Pharmacological Phenomena

