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Updated: Jan 21, 2026

Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy
Published on: January 29, 2022
Investigation of chloramphenicol release from PVA/CMC/HEA hydrogel using ion beam analysis, UV and FTIR techniques
M S Rihawy1, A Alzier2, A W Allaf2
1Department of Physics, Atomic Energy Commission, P.O. Box 6091, Damascus, Syrian Arab Republic.
Abstract:
PVA/CMC/HEA based cross-linked hydrogels were synthesized. These were utilized as matrix chloramphenicol drug releasing systems. Combination of different analytical techniques was applied to understand drug releasing process. Ion beam analysis (IBA) measurements, namely micro-PIXE analysis, were applied to gain information regarding spatial distribution of chloramphenicol within the system. Independent complement measurements utilizing UV and pore volume measurements were also employed to additionally characterize and verify the experimental findings obtained by IBA techniques. FTIR was utilized to both characterize and justify the releasing behavior of the crosslinked systems. Comprehensive literature comparison between different analytical methods has been reviewed.
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