Long-term outcomes of functional neurological disorder in children

Joseph Raper1, Victoria Currigan1, Sarah Fothergill2

  • 1Paediatric Neurology, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Insights

Functional neurological disorder (FND) in children is more common than previously thought. While many children experience symptom remission, a significant portion may develop FND or similar symptoms in adulthood.

Area of Science:

  • Neurology
  • Pediatrics
  • Psychiatry

Background:

  • Functional neurological disorder (FND) is a common reason for pediatric neurology referrals.
  • Long-term outcomes and adult recurrence rates for pediatric FND are not well-established.

Purpose of the Study:

  • To determine the incidence of pediatric FND.
  • To investigate the long-term outcomes of pediatric FND, including adult symptom recurrence.

Main Methods:

  • Retrospective chart review of pediatric neurology patients with FND.
  • Record linkage with Child and Adolescent Mental Health Services.
  • Review of adult medical records for functional symptoms.

Main Results:

  • 124 children met criteria; common presentations included seizures, sensory loss, and motor symptoms.
  • Incidence in pediatric neurology services was 6 per 100,000 children under 16.
  • Over a median follow-up of 8.3 years, 23% of eligible individuals showed evidence of FND in adulthood.

Conclusions:

  • Pediatric FND is more common than previously estimated.
  • Despite specialist referral, a high long-term remission rate is observed in this pediatric FND cohort.
Abstract

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