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Updated: Jan 21, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Quantification of accommodative response and visual performance in non-presbyopes wearing low-add contact lenses
Shizuka Koh1, Ryota Inoue2, Shinnosuke Sato3
1Department of Innovative Visual Science, Osaka University Graduate School of Medicine, Osaka, Japan; Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan.
Purpose:
Digital eye strain encompasses a range of ocular and visual symptoms across all age groups. Recently, symptoms associated with accommodative or binocular vision stress have become a major problem, especially in young individuals. The purpose of this prospective, single-blinded study was to objectively quantify the accommodative response and visual performance of low-add soft contact lenses (CLs) in young non-presbyopic individuals.
Methods:
A daily disposable low-add bifocal design lens (low-add CL) was tested. It employs a centre-distance optical zone and peripheral zone with the added power of +0.50 D to support near vision. Sixteen subjects aged 20-39 years were enrolled in the study. Refractive state and accommodation were measured using an open-field autorefractor with three target vergences, namely, -0.20 D, -2.5 D, and -4.0 D. Binocular visual acuity at high (100%) and low (40%, 20%) contrast and reading ability were assessed. Monofocal soft CLs were used as controls.
Results:
Accommodative response with low-add CLs was significantly smaller than those with two monofocal CL wearing conditions, i.e., at 40 cm (2.5 D of stimulus) and 25 cm (4.0 D of stimulus) (all p < 0.05). The 20% contrast visual acuity at distance was significantly better with low-add CLs and second-time monofocal CLs compared to first-time monofocal CLs (all p < 0.05). The reading ability was not significantly different.
Conclusions:
Quantification of accommodative response and visual performance demonstrated that using low-add CLs alleviated the accommodation under the near-vision condition, without sacrificing distance vision, in non-presbyopes.
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